Immunohistochemistry Kits and Reagents
Rockland Immunochemicals Fluorescent Activated Cell Sorting (FACS) and Immunofluorescence (IF) Staining Buffer with BSA - MB-089-0500
Fluorescent Activated Cell Sorting (FACS) and Immunofluorescence (IF) staining buffer is a diluent buffer optimized for use in flow cytometry and immunofluorescence assay of viable and/or fixed cells. FACS and IF staining, washing buffer contains 1% BSA as carrier and stabilizer to reduce non-specific binding of antibodies and fluorochrome reagents to targets cells. Metabolic inhibitors and NaN3 are also included in the flow cytometry and immunofluorescence buffer to prevent patching, capping of surface antigen and bacterial growth.
ABclonal Technology GSTT1 Rabbit mAb
The protein encoded by this gene glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds Human GSTs can be divided into five main classes alpha mu pi theta and zeta The theta class includes GSTT1 GSTT2 and GSTT2B GSTT1 and GSTT2 GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis The GSTT1 gene is haplotype-specific and is absent from 38% of the population Alternative splicing of this gene results in multiple transcript variants
Leica Biosystems AVIDIN/BIOTIN BLOCKING SYSTEM
Some tissues may bind avidin, biotinylated horseradish peroxidase, biotinylated alkaline phosphatase or other Biotin/Avidin System components without prior addition of biotinylated antibody. This binding may be due to endogenous biotin or biotin-binding proteins, lectins or non-specific binding substances present in the section. If high background is present using Avidin Biotin Complex (ABC) reagents, or other avidin conjugates in the absence of biotinylated secondary antibody, the use of the Novocastra Avidin/Biotin Blocking System RE7170-K may be of benefit. 18 mL of each of avidin and biotin are supplied. For research use only.
Medchemexpress LLC METTL1 protein, human (His-tagged) | >95.0% | 50 UG
Recombinant human METTL1 (residues D32-Q265) with an N-terminal His tag, provided as purified protein for biochemical and structural studies. The protein represents the catalytic component of the METTL1-WDR4 methyltransferase complex and is intended for use in enzymology, binding assays, and molecular biology applications.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Molecular weight approximately 30 kDa.
- N-terminal His tag to facilitate purification and detection.
- Amino acid range D32-Q265 corresponding to the mature catalytic domain.
- Store at -80°C for long-term storage; stable at -20°C up to 3 months; avoid repeated freeze-thaw cycles.
Abcam Rabbit specific HRP/AEC IHC Detection Kit - Micro-polymer, 15ML
This IHC detection kit is used to detect rabbit primary antibodies in immunohistochemistry (IHC).
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical p38 MAPK InhIbItr IV 10mg
An ATP-competitive inhibitor of p38 MAPKs; inhibits p38α, p38β, p38��, and p38δ MAPKs (IC50s = 0.13, 0.55, 5.47, and 8.63 μM, respectively); inhibits LPS-induced TNF-α and IL-1β cytokine production in human peripheral blood mononuclear cells (IC50s = 22 and 44 nM, respectively)
ABclonal Technology Desmin Rabbit pAb
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
ACROBiosystems Biotinylated Human Nectin-4 (244-349) Protein, His, AviTag (MALS verified)
Biotinylated human Nectin-4 extracellular domain (amino acids 244-349) is produced in HEK293 cells with an N-terminal polyhistidine tag and an AviTag; the AviTag is enzymatically labeled with biotin. The reagent is provided lyophilized and is suitable for binding assays, receptor-ligand studies, and detection applications.
- Amino acid range: Phe 244-Ser 349.
- Expression system: Human 293 cells (HEK293).
- Tags: N-terminal polyhistidine tag and AviTag.
- Biotinylation: Enzymatic biotin labeling of the AviTag lysine residue.
- Purity: Greater than 95% as determined by SEC-MALS and SDS-PAGE.
- Molecular weight: Calculated 15.2 kDa; migrates ~18 kDa and 19-25 kDa on reducing SDS-PAGE due to glycosylation.
- Available sizes: 25 μg and 200 μg.
- Storage: Lyophilized, stable at -20°C to -70°C for 12 months; reconstituted product stable at -70°C for 3 months.
ABclonal Technology Phospho-p38 MAPK-T180 Rabbit pAb
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Seracare Life Sciences Inc CONTRAST BLUE SOLUTION
Contrast BLUE Solution for Immunohistochemistry contains hematoxylin. It is designed for use as a counterstain with the HistoMark immunohistochemical staining systems.
Seracare Life Sciences Inc TMB BLUESTOP SOLUTION
TMB BlueSTOP Solution is formulated to stop color development in microwell assays and maintain the blue color of TMB. Unlike traditional acid-based TMB stopping solutions, the O.D. value of TMB does not change upon addition of TMB BlueSTOP. The stopped substrate is stable for an extended period and can be read at 650 nm. TMB BlueSTOP is ideal for use with KPL's microwell peroxidase substrates, SureBlue and SureBlue Reserve 1-Component TMB, and TMB 2-Component Microwell Peroxidase Substrate. The reagent is supplied as a convenient, ready-to-use solution that is stable for a minimum of one year.
Vector Laboratories Vector M.O.M. Kit (Mouse-On-Mouse) Immunodetection Kit
Vector M.O.M. Kits contain a proprietary Mouse IgG Blocking Reagent that greatly reduces endogenous mouse IgG background when staining mouse primary antibodies on mouse tissue. Vector M.O.M. Immunodetection Kits are useful in any mouse-on-mouse application, such as studies in genetically engineered mice, including transgenic and knock-out models, and mouse xenografts. M.O.M. Kits can be also used in multiple antigen staining protocols to localize two different mouse primary antibodies on the same mouse tissue sections using fluorescent or enzyme-based detection systems. The M.O.M. Basic Kit is designed to be used with a user-provided horseradish peroxidase, alkaline phosphatase, or fluorescent dye-labeled avidin or streptavidin conjugate that is compatible with M.O.M. Biotinylated Anti-Mouse IgG secondary antibody.
Biocare Medical, LLC Pan Melanoma + Ki-67 Antibody - Predilute, 25 ml
Pan Melanoma Antibody Ki-67 serves as a tool to identify the proliferation rate of melanocytic lesions in cases in which melanocytes are sparse; there are dense lymphocytic infiltrates; and melanocytes are admixed with fibroblasts. In general, a higher proliferative fraction is seen in melanoma than in melanocytic nevi. There are many types of nevi, and some simulate melanoma closely. If the Multiplex stain shows a very low Ki-67 (DAB) labeling rate in MART-1/Tyrosinase positive cells (Fast Red), this favors benignity. A high rate, especially toward the deep part of a melanocytic lesion raises the possibility of malignancy.
ABclonal Technology Phospho-p38 MAPK-Y182
The protein encoded by this gene is a member of the MAP kinase family MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development This kinase is activated by various environmental stresses and proinflammatory cytokines The activation requires its phosphorylation by MAP kinase kinases (MKKs) or its autophosphorylation triggered by the interaction of MAP3K7IP1 TAB1 protein with this kinase The substrates of this kinase include transcription regulator ATF2 MEF2C and MAX cell cycle regulator CDC25B and tumor suppressor p53 which suggest the roles of this kinase in stress related transcription and cell cycle regulation as well as in genotoxic stress response Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
Abcam TripleStain IHC Kit: M&R&Rt on rodent tissue (DAB, DAB/Ni & AP/Red), 6ML
The TripleStain IHC Kit (ab183298) is designed to be used with user-supplied mouse, rat and rabbit primary antibodies to detect three distinct antigens on mouse tissue and cell samples or human tissue.
The product is subject to the following: Abcam Restricted Use Statement